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Showing posts with the label Neuro-Anatomy

Uncertainty in Multiclass Classification

1. What is Uncertainty in Classification? Uncertainty refers to the model’s confidence or doubt in its predictions. Quantifying uncertainty is important to understand how reliable each prediction is. In multiclass classification , uncertainty estimates provide probabilities over multiple classes, reflecting how sure the model is about each possible class. 2. Methods to Estimate Uncertainty in Multiclass Classification Most multiclass classifiers provide methods such as: predict_proba: Returns a probability distribution across all classes. decision_function: Returns scores or margins for each class (sometimes called raw or uncalibrated confidence scores). The probability distribution from predict_proba captures the uncertainty by assigning a probability to each class. 3. Shape and Interpretation of predict_proba in Multiclass Output shape: (n_samples, n_classes) Each row corresponds to the probabilities of ...

Pedunculopontine Nucleus (PPN)

The Pedunculopontine Nucleus (PPN) is a group of neurons located in the brainstem, specifically in the pontine region. Here is an overview of the Pedunculopontine Nucleus: 1.       Anatomy : o The PPN is situated in the rostral part of the brainstem, near the junction of the pons and midbrain. It is part of the reticular formation, a network of neurons involved in various physiological functions. o The PPN receives inputs from multiple brain regions, including the basal ganglia, thalamus, and cortex, and sends outputs to structures involved in motor control, arousal, and gait. 2.      Function : o Motor Control: The PPN is implicated in the regulation of motor functions, particularly in the control of posture, locomotion, and movement initiation. It is involved in coordinating rhythmic movements and adjusting gait patterns. o Arousal and Attention: The PPN is also associated with arousal, wakefulness, and attention. It plays a role in regulat...

Pontomedullary Reticular Formation (PmRF)

The Pontomedullary Reticular Formation (PMRF) is a complex network of neurons located in the brainstem, specifically in the pontine and medullary regions. Here is an overview of the PMRF: 1.       Anatomy : o The PMRF is part of the reticular formation, a network of interconnected nuclei and pathways that extends throughout the brainstem. It is situated in the pontine and medullary regions, which are important for regulating various physiological functions. o The PMRF is involved in the modulation of motor functions, sensory processing, cardiovascular control, respiratory rhythm, and the sleep-wake cycle. 2.      Function : o Motor Control: The PMRF plays a crucial role in the coordination of voluntary movements and postural control. It receives inputs from higher brain centers and projects to the spinal cord and cranial nerve nuclei to influence motor output. o   Sensory Processing: The PMRF is involved in sensory integration and modula...