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Showing posts with the label Research Methodology & Biostats

Energy Manifold Natural Gradient Descent: From Riemannian Optimization to Modern Neuroscience, NeuroAI and Quantum Physics

When Geometry, Energy, Artificial Intelligence and Neuroscience Converge Modern Artificial Intelligence is rapidly moving beyond the idea that learning simply means minimizing an error function. Increasingly, researchers are asking a deeper question: what is the structure of the space in which learning takes place? This question becomes particularly important when the system being modelled is constrained, nonlinear, dynamic, or governed by physical principles. A recent work titled “Energy Manifold Natural Gradient Descent: Riemannian Optimization for Neural PDE Solvers” , by Zhangyong Liang and Huanhuan Gao, introduces Energy Manifold Natural Gradient Descent (EMNGD) , a mathematical framework that extends energy-based natural-gradient optimization from unconstrained Euclidean parameter spaces to constrained Riemannian parameter manifolds . At its core, the framework proposes a simple but powerful principle: An optimization algorithm should not only determine how to reduce error; it sh...

Robotics in Neurorehabilitation: Beyond the Hype—Understanding What It Can (and Cannot) Do

Over the past decade, robotic neurorehabilitation has become one of the most discussed innovations in neurological recovery. Robotic gait trainers, upper-limb rehabilitation systems, exoskeletons, and AI-assisted rehabilitation devices are increasingly being adopted by hospitals and rehabilitation centres worldwide. However, an important question remains: Are robots the future of neurorehabilitation—or are they simply another tool in the rehabilitation toolbox? As clinicians and researchers, we must move beyond marketing claims and focus on scientific evidence, patient selection, and clinical reasoning. What is Robotic Neurorehabilitation? Robotic neurorehabilitation involves the use of electromechanical devices that assist, guide, resist, or augment movement during therapy. These technologies include: • Robotic gait trainers • Wearable exoskeletons • Upper limb robotic rehabilitation devices • End-effector robotic systems • Sensor-based rehabilitation platforms • AI-assiste...

How to Select a Random Sample?

Selecting a random sample is a crucial aspect of research methodology to ensure the representativeness and generalizability of study findings. Here are some common methods and considerations for selecting a random sample: 1.     Simple Random Sampling : o     In simple random sampling, each element in the population has an equal chance of being selected for the sample. o     One method is to assign a unique identifier (e.g., numbers) to each element in the population and then use a random number generator to select sample units. o     Another approach is to use random sampling techniques such as lottery methods or random number tables to choose sample units. 2.     Systematic Sampling : o     In systematic sampling, researchers select every nth element from a list of the population after randomly determining a starting point. o     This method is efficient and easy to implement, espe...

Judgement Sampling

Judgment sampling, also known as purposive or selective sampling, is a non-probability sampling technique where researchers use their judgment and expertise to select sample units based on specific criteria or characteristics relevant to the research objectives. In judgment sampling, researchers intentionally choose sample units that they believe are representative or typical of the population of interest. Here are some key points about judgment sampling: 1.     Definition : §   Judgment sampling is a non-probability sampling method where researchers select sample units based on their judgment, expertise, or knowledge of the population. §   Sample units are chosen deliberately to represent certain traits, characteristics, or experiences that are deemed relevant to the research objectives. 2.     Characteristics : §   Judgment sampling relies on the researcher's subjective judgment and understanding of the population to select sample units tha...

Quota Sampling

Quota sampling is a non-probability sampling technique that involves dividing the population into subgroups or strata based on certain characteristics and then selecting samples from each subgroup in proportion to their presence in the population. Quota sampling is a method of convenience sampling where researchers establish quotas for different subgroups and then non-randomly select participants to fill those quotas. Here are some key points about quota sampling: 1.     Definition : o   Quota sampling is a non-probability sampling method where researchers divide the population into subgroups or strata based on specific characteristics (such as age, gender, income level) and then set quotas for each subgroup. o     Participants are selected non-randomly to fill the quotas, typically based on convenience or availability, rather than through random selection. 2.     Process : o     Researchers first identify key characterist...