3D-0D closed-loop model for the simulation of cardiac biventricular electromechanics

The article presents a comprehensive study on a 3D-0D closed-loop model for simulating biventricular electromechanics in the context of the heart and circulatory system interaction. The model incorporates detailed descriptions of the muscular fiber architecture within the heart to accurately represent cardiac activity. By considering the interaction between the left and right ventricles, the study highlights the importance of a biventricular approach over a stand-alone left ventricle model. The model accounts for active tension along different directions within the heart, showing how it impacts cardiac work and efficiency. Additionally, the article discusses the distribution of stress on the ventricular base and the implications of different stress distribution approaches. Overall, the study emphasizes the significance of a holistic approach to simulating cardiac electromechanics, considering both ventricles and their interplay within the cardiovascular system.

Piersanti, R., Regazzoni, F., Salvador, M., Corno, A. F., Dede', L., Vergara, C., & Quarteroni, A. (2021). 3D-0D closed-loop model for the simulation of cardiac biventricular electromechanics. *arXiv preprint arXiv:2108.01907*.

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